Hens have shown to be an excellent provider of antibodies towards the new Corona virus.
At Ovodan Biotech we have examined the immune response of several antigens, and now we are able to offer high affinity polyclonal chicken antibodies towards the SARS-CoV-2 Spike Receptor Binding Domain.
Kinetic measurements of the anti-SARS-CoV-2 Spike RBD IgY indicate a Kd of the affinity purified antibodies in a single-digit nanomolar range. This is impressive for a polyclonal antibody product. And it offers good opportunities to develop rapid tests that are highly sensitive and specific.
Chicken antibodies do not recognize protein A or protein G as mammal IgG. This means that using avian antibodies in your test you can avoid false positives, and consequently improve the specificity..
Additionally, the IgY Fc-region provides two sites for labelling. Utilizing this advantage, LOD might be markedly improved by including IgY in your immuno assay.
Have closer look at the datasheet for the Ovodan Biotech anti-SARS-CoV-2 Spike RBD IgY here: